THROMBOSIS AND HEMOSTASIS A humanized single-chain antibody against beta 3 integrin inhibits pulmonary metastasis by preferentially fragmenting activated platelets in the tumor microenvironment

نویسندگان

  • Wei Zhang
  • Suying Dang
  • Tao Hong
  • Jian Tang
  • Jing Fan
  • Dawei Bu
  • Yanjie Sun
  • Zhugang Wang
  • Thomas Wisniewski
چکیده

1Institutes for Advanced Interdisciplinary Research, East China Normal University, Shanghai, People’s Republic of China; 2Shanghai Engineering Research Center of Molecular Therapy and Pharmaceutical Innovation, Shanghai, People’s Republic of China; 3Department of Medical Genetics, Shanghai Jiao Tong University School of Medicine, Shanghai, People’s Republic of China; 4Shanghai Key Laboratory of Brain Functional Genomics, East China Normal University, Shanghai, People’s Republic of China; and Departments of 5Neurology, 6Pathology, and 7Psychiatry, New York University School of Medicine, New York, NY

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تاریخ انتشار 2012